Home > Topics > American Heart Association Recommendations for Duration of Secondary Prophylaxis : Harrison 18e Update

American Heart Association Recommendations for Duration of Secondary Prophylaxis : Harrison 18e Update

October 13, 2011

Rheumatic fever without carditis
For 5 years after the last attack or 21 years of age (whichever is longer)

Rheumatic fever with carditis but no residual valvular disease
For 10 years after the last attack, or 21 years of age (whichever is longer)

Rheumatic fever with persistent valvular disease, evident clinically or on echocardiography
For 10 years after the last attack, or 40 years of age (whichever is longer). Sometimes lifelong prophylaxis

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